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With a fresh $10 million in the bank, DotLab hopes to bring endometriosis test to market – TechCrunch

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Thirty-three-year-old founder of personalized medicine company DotLab, Heather Bowerman, wants to shake up the women’s health industry with what she believes to be a better, cheaper, less painful test for endometriosis.

Her company has just completed a Yale University -led validation study and raised $10 million in Series A funding from CooperSurgical, TigerGlobal Management, Luxor Capital Group and the law firm Wilson Sonsini Goodrich & Rosati to bring a new, non-invasive diagnostic test to market.

Endometriosis is an often painful disorder in which tissue begins to grow outside of the uterus and into a woman’s ovaries, fallopian tubes and pelvis. The disease may affect up to one in 10 women of childbearing years and about half of all women who experience infertility, according to the U.S. Department of Health and Human Services.

However, even with clear symptoms of the disease, doctors often try to test for endometriosis as a last resort. The only way currently to test for it is through an invasive laparoscopic procedure, which comes with risks like internal bleeding, infections and hernia.

Called DotEndo the new DotLab test eliminates that risk with a simple diagnostic test. “The rationale for using our test is to test as early as possible and also to use it non-invasively,” Bowerman told TechCrunch.

The CEO was also quick to point out DotEndo is not a genetic test, as there are plenty of tests out on the market helping women discover possible genetic markers around fertility. Rather, it’s a physician-ordered diagnostic test you would take through a lab to find out if you have this specific disease.

“The revolutionary technology behind DotLab’s endometriosis test could improve the lives of the hundreds of millions of women affected by this debilitating disease which has been under-researched and deprioritized for too long,” Bowerman said in a statement.

While there has been some innovation in the space lately — U.S. regulators just approved a new pill to treat endometriosis pain — Bowerman is right in that we definitely still have a long way to go in diagnosing and curing the disease and that will take a lot more capital from investors in the future.

Meanwhile, the next step for DotLab will be to get its test into the hands of physicians, with the hope they recommend DotEndo right off the bat to patients exhibiting symptoms.

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12 Best Uses For Old Computer Keyboards

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Maybe you want to wear your love of keyboards on your sleeve, but earrings and charm bracelets are just a little too ostentatious for your taste. Enter the subtler and more stylish buttons and cufflinks. Not only is this a more discreet way of keeping your old keyboard close, but it’s also among the easiest projects we have for you.

You’ll only need a few supplies, at least one of which you already have at hand. There aren’t any scissors or saws, and you won’t be using any power tools. All you need is your old keyboard, an adhesive like epoxy, and the base of a cufflink or button, both of which you can find at your local craft store or online.

Before you get started, however, take a moment to inspect your keyboard. Consider the wide array of buttons, each with its own special function. Now choose your favorites. Those are the keys you want to carefully remove. If you’re making cufflinks, you’ll need at least two keys. If you’re making buttons, the sky’s the limit.

Now take out a flathead screwdriver — the only tool you’re going to need — and pop the keys you’ve chosen off of the keyboard frame. Once you’ve got them all liberated, generously apply adhesive to the back side of each key and jam the cufflink or button base right in there. Wait for it to cure and you’re ready to attach them to your favorite threads.

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28% Of Car Lovers Most Want To Own This Banned Vehicle

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In a SlashGear poll with 590 U.S. respondents, 27.97% said they would love to own Lamborghini Diablo Strosek. The Italian supercar is not street legal in the U.S. because it’s too fast. If pushed to the limit, the Lamborghini Diablo can exceed 200 mph — this made it the fastest car when it was released in 1990. But it was a German designer known as Vittorio Strosek who modified it and made it even more difficult for it to pass the FMVSS regulations. Because of the 25-year rule, you’re only allowed to import a Lamborghini Diablo that was produced between 1990 to 1997.

The second most popular option in the poll was the Porsche 959, which was picked by 25.25% of the respondents. Just like Lamborghini Diablo, Porsche 959 is super-fast but it doesn’t exceed 200 mph — the best it can do is 198 mph in the Sport variant. However, the real reason Porsche 959 was never sold in the U.S. is that the automaker didn’t want to have its very expensive cars crash tested by NHTSA. Despite the Porsche 959 quickly selling out after it was released, the manufacturer was making a loss selling the car — and if NHTSA crash tested a minimum of four cars, it would have lost more money.

Besides that, 19.83% of the participants said they would prefer Honda ATC and 16.95% wanted Nissan GT-R Skyline. The Smart Crossblade was the least popular option at 10%. 

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The Reason Why NYC Destroys Hundreds Of Dirt Bikes And ATVs Each Year

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In 2021, eight people were killed by dirt bikes or ATVs, and the New York Police Department, along with then-Mayor Bill de Blasio, went on a crusade to get rid of illegal vehicles, according to The City. By the end of the year, the city had seized and subsequently destroyed approximately 500 bikes. As many as 3,000 were ultimately crushed under the tracked wheels of a bulldozer in 2021 (via The City).

When new Mayor Eric Adams took office on January 1, 2022, he continued the fight. By June, they had seized over 2,000 bikes — almost 80% over the number they took by that time the previous year. And there’s no sign of letting up, with the police nabbing more than 250 on a single Sunday in August.

The dirt bikes and ATVs are not street legal to begin with, lacking several required features like turn signals, brake lights, and mirrors. According to the New York Department of Motor Vehicles, any 1985 or newer motorcycle must be equipped with directional or turn signals that show amber to the front and red or amber to the rear. It must also have an adjustable rear view mirror, a red stop lamp on the back, and a headlamp on the front of the vehicle. None of these things are found on a vast majority of the illegal vehicles that, as Mayor Adams put it, are continuing to terrorize the city.

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